Sunday, September 30, 2012

Afghan forces also suffer from insider attacks

FILE - In this July 9, 2010 file photograph, an Afghan National Army soldier wears an ammunition belt around his neck during a joint patrol with United States Army soldiers from Bravo Company, 2nd Battalion of the 508 Parachute Infantry Regiment of the 82nd Airborne, in the volatile Arghandab Valley, outside Kandahar City. U.S. military officials have noted that Afghan security forces are dying in insider attacks along with foreign troops, but so far, the Afghan government has not provided statistics on the number killed. (AP Photo/Kevin Frayer, File)

FILE - In this July 9, 2010 file photograph, an Afghan National Army soldier wears an ammunition belt around his neck during a joint patrol with United States Army soldiers from Bravo Company, 2nd Battalion of the 508 Parachute Infantry Regiment of the 82nd Airborne, in the volatile Arghandab Valley, outside Kandahar City. U.S. military officials have noted that Afghan security forces are dying in insider attacks along with foreign troops, but so far, the Afghan government has not provided statistics on the number killed. (AP Photo/Kevin Frayer, File)

FILE - In this Oct. 3, 2009 file photo, U.S. Marine squad leader Sgt. Matthew Duquette, left, of Warrenville, Ill., with Bravo Company, 1st Battalion 5th Marines walks with Afghan National Army Lt. Hussein, during in a joint patrol in Nawa district, Helmand province, southern Afghanistan. U.S. military officials have noted that Afghan security forces are dying in insider attacks along with foreign troops, but so far, the Afghan government has not provided statistics on the number killed. (AP Photo/Brennan Linsley, File)

KABUL, Afghanistan (AP) ? Afghan Army Sgt. Habibullah Hayar didn't know it, but he had been sleeping with his enemy for weeks.

Twenty days ago, one of his roommates was arrested for allegedly plotting an insider attack against their unit, which is partnered with NATO forces in eastern Paktia province.

Afghan soldiers and policemen ? or militants in their uniforms ? have gunned down more than 50 foreign troops so far this year, eroding the trust between coalition forces and their Afghan partners. An equal number of Afghan policemen and soldiers also died in these attacks, giving them reason as well to be suspicious of possible infiltrators within their ranks.

"It's not only foreigners. They are targeting Afghan security forces too," said the 21-year-old Hayar, who was in Kabul on leave. "Sometimes, I think what kind of situation is this that a Muslim cannot trust a Muslim ? even a brother cannot trust a brother. It's so confused. Nobody knows what's going on."

The U.S.-led coalition said a NATO service member and an international civilian contractor were killed on Saturday in the latest such insider attack. The coalition said in a statement on Sunday that Afghan soldiers were also killed or wounded, but provided no other details about the attack in eastern Afghanistan.

Insider attacks are taking a toll on the partnership, prompting the U.S. military to restrict operations with small-sized Afghan units earlier this month.

The close contact ? with coalition forces working side by side with Afghan troops as advisers, mentors and trainers ? is a key part of the U.S. strategy for putting the Afghans in the lead as the U.S. and other nations prepare to pull out their last combat troops at the end of 2014, just 27 months away.

The U.S. military also has shown increasing anger over the attacks.

"I'm mad as hell about them, to be honest with you," Gen. John Allen, the top commander of U.S. and NATO forces in Afghanistan, told CBS' "60 Minutes" in an interview scheduled to be broadcast on Sunday. "It reverberates everywhere across the United States. You know, we're willing to sacrifice a lot for this campaign, but we're not willing to be murdered for it."

So far this year, at least 52 foreign troops ? about half of them Americans ? have been killed in insider attacks. The Afghan government has not provided statistics on the number of its forces killed in insider attacks. However, U.S. military statistics obtained by The Associated Press show at least 53 members of the Afghan security forces had been killed as of the end of August.

A U.S. military official disclosed the numbers on condition of anonymity because he said it was up to Afghan officials to formally release the figures. An Afghan defense official who was shown the statistics said he had no reason to doubt their accuracy.

Overall, the statistics show that at least 135 Afghan policemen and soldiers have been killed in insider attacks since 2007. That's more than the 119 foreign service members ? mostly Americans ? killed in such attacks since then, according to NATO.

Typically, foreign troops are the main targets, but Afghan forces also have been killed by comrades angry over their collaboration with Westerners and many more get killed in the crossfire, Defense Ministry spokesman Gen. Zahir Azimi said. He said the ministry did not have a breakdown of how many had been targeted or killed in gunbattles during the attacks.

In at least one instance, an Afghan police officer with alleged ties to militants, killed 10 of his fellow officers on Aug. 11 at a checkpoint in southwestern Nimroz province. An Afghan soldier also was killed on April 25 when a fellow soldier opened fire on a U.S. service member and his translator in Kandahar province, the southern birthplace of the Taliban.

Last year, a suicide bomber in an Afghan police uniform blew himself up May 28 in Takhar province, killing two NATO service members and four Afghans, including a senior police commander. And just a week before that, four Taliban fighters wearing suicide vests under police uniforms attacked a government building in Khost province, triggering a gunbattle that left three Afghan policemen and two Afghan soldiers dead. On April 16, an Afghan soldier walked into a meeting of NATO trainers and Afghan troops in Laghman province, blew himself up, killing five U.S. troops, four Afghan soldiers and an interpreter.

"It's difficult to know an attacker from a non-attacker when everybody is wearing a uniform, Hayar said.

The attacker was one of seven people rounded up earlier this month from various units within the Afghan National Army Corps 203, Hayar said. The corps covers the eastern Afghan provinces of Paktia, Paktika, Ghazni, Wardak, Logar and Khost.

"He was together with me in my room with some of my other colleagues. He had a long beard. We didn't know anything about him. We were living together, sleeping together," said Hayar, who has been in the Afghan army for 2 1/2 years.

He said the suspected infiltrator was identified after a Taliban militant arrested in Logar told his Afghan interrogators that members of the fundamentalist Islamic movement had infiltrated the corps and were planning imminent attacks. That prompted Hayar's superiors to start questioning soldiers in various units.

Hayar said his roommate's uneasy reaction raised suspicion, and investigators found Taliban songs saved to the memory card of his cell phone. He was then detained by Afghan intelligence officials and confessed he was a member of the Taliban and planned to stage attacks.

Hayar says he assumes his former bunkmate was probably going after foreign forces, but it makes him uncomfortable nevertheless.

"It's very hard to trust anybody ? even a roommate," he said. "Whenever I'm not on duty, I lock my weapon and keep the key myself. I don't put my weapon under my pillow to sleep because maybe someone will grab it and shoot me with my own weapon."

To counter such attacks, the U.S. military earlier this year stopped training about 1,000 members of the Afghan Local Police, a controversial network of village-defense units. U.S. commanders have assigned some troops to be "guardian angels" who watch over their comrades even as they sleep. U.S. officials also recently ordered American troops to carry loaded weapons at all time, even when they are on their bases.

Then, after a string of insider attacks, Allen this month restricted operations carried out alongside with small-sized Afghan units. Coalition troops have routinely conducted patrols or manned outposts with small groups of Afghan counterparts, but Allen's directive said such operations would no longer be considered routine and required the approval of the regional commander.

For their part, Afghan authorities have detained or removed hundreds of soldiers as part of its effort to re-screen its security forces. The Ministry of Defense also released a 28-page training booklet this month that advises soldiers not to be personally offended when foreign troops do things Afghans view as deeply insulting.

The booklet urges them not to take revenge for foreign troops' social blunders, such as blowing their noses in public, stepping into a mosque with their shoes on, walking in front of a soldier who is praying or asking about their wives.

"Most of the coalition members are interested to share pictures of their families. It is not a big deal for them. If someone asks you about your family, especially the females in your family, don't think they are disrespecting you or trying to insult you," the booklet says.

"That is not the case. By asking such questions, they are trying to show that they want to learn more about you. You can very easily explain to them that nobody in Afghanistan would ask, especially about wives or females in the family."

___

Associated Press writers Amir Shah and Rahim Faiez in Kabul contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-09-30-Afghan-Insider%20Attacks/id-e65bbd96bca4407ebbcd9b90e8adf413

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Provision Of Running Of Animal Hospital In Gogawa Division, District Khargone A Bhopal

Director of Directorate of Animal Husbandry, Bhopal, Madhya Pradesh invites tenders notice for provision of running of animal hospital in Gogawa division, district Khargone. Tender document can be collected/downloaded from Directorate of Animal Husbandry, Bhopal .

Free tenders email alerts

Source: http://feedproxy.google.com/~r/indiamart/tenders/medical-pharma/~3/9eKlfeiC2Vw/

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Kazakhstan gets first Saks Fifth Avenue store

NEW YORK (Reuters) - Saks Inc opened its first Saks Fifth Avenue store in Kazakhstan on Sunday, as the retailer seeks to tap a growing appetite for luxury in emerging markets.

The tri-level, 91,000-square-foot (8,450-square-meter) store is located in the Esentai Shopping Mall, the first of its kind in Kazakhstan, Saks said in a news release.

The mall is part of Esentai Park, a new development in Almaty that includes luxury residential and commercial towers as well as a five-star hotel that is expected to open next year.

The Saks store is being licensed by the VILED Group, a local company.

Oil- and uranium-producing Kazakhstan is Central Asia's largest economy. Foreign investors have poured more than $150 billion into the country during its two decades of independence from the old Soviet Union.

(Reporting by Martinne Geller; Editing by Dale Hudson)

Source: http://news.yahoo.com/kazakhstan-gets-first-saks-fifth-avenue-store-174439352--finance.html

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Saturday, September 29, 2012

TGen and Scottsdale Healthcare report first study of clonal evolution in Maxillary Sinus Carcinoma

TGen and Scottsdale Healthcare report first study of clonal evolution in Maxillary Sinus Carcinoma [ Back to EurekAlert! ] Public release date: 28-Sep-2012
[ | E-mail | Share Share ]

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Examination of sinus cavity tumor provides potential roadmap for rare cancer treatments

PHOENIX, Ariz. Sept. 28, 2012 Knowing how tumors evolve can lead to new treatments that could help prevent cancer from recurring, according to a study published today by the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare.

TGen researchers tracked several years of tumor evolution in a 47-year-old male patient with maxillary sinus carcinoma (MSC), a rare cancer of the sinus cavities beneath the cheeks that often requires surgical removal that is disfiguring. Fewer than half of MSC patients live more than 5 years after diagnosis.

"The ability to characterize clonal evolution of this rare cancer and identify its Achilles' heel can significantly impact treatment, leading to more personalized medicine," according to the study published today in the journal PLOS ONE.

Clonal evolution refers to the often-rapid genetic changes that occur in cancer cells, which continually mutate and, thus, frequently resist anti-cancer drug compounds intended to destroy them.

"If we can understand the genomic basis of how this cancer evolves, perhaps we can find new treatments that could help improve the longevity and quality of life for patients," said Dr. Glen Weiss, Clinical Associate Professor at TGen, and Director of Thoracic Oncology at Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, a partnership with TGen. Dr. Weiss is one of the study's senior co-authors.

MSC represents nearly four of every five cases of paranasal sinus cancers, which grow rapidly and invade nearby tissues but also are usually slow to spread to distant sites. Patients usually die from a local recurrence of the tumor, even after aggressive treatment.

"This is the first report to study the clonal population of MSC arising in longitudinal samples from the same patient," the study said. "One of the aims of this study was to closely follow disease progression and the clonally evolving metastases for molecular profiling and accumulation of data for future use in development of personalized treatment."

The patient in the study received conventional treatment, which included surgical removal of his tumors, radiation therapy and chemotherapy, and participation in a clinical trial.

Over time, however, the cancer spread to his upper right lung, lower left lung, left kidney, brain and part of his intestine. He eventually was hospitalized, received hospice care and prior to passing away gave permission to have his cancer studied after death in a rapid autopsy research program.

"Because his cancer resumed growth despite several courses of systemic chemotherapy and radiation therapy, we speculated that acquired secondary genetic changes evolved with the evolution of resistance to these therapies," said Dr. Michael Barrett, Associate Professor in TGen's Clinical Translational Research Division, and the study's other senior co-author.

Analysis of his tumors following surgeries, biopsies and autopsy revealed several genetic aberrations, including multiple copies of a region on chromosome 4q, which includes the KIT gene. KIT is an oncogene, a gene with the potential to cause cancer, and is a potential treatment target.

The authors suggest the results provide a unique description of how the drug resistant cancer cells replicate and progress to metastatic MSC. Additional findings included the loss of the gene PKP4, which is associated with increased tumor size.

"These results show that molecular analyses of patient samples can add to the information about the tumor and help us in tracking back the progression of the disease," the authors concluded. "Identification of selected genetic changes, and the biological processes they regulate arising in primary MSC tumors, will advance individualizing therapy and improve the outcome of patients with rare cancers."

"These kinds of cutting-edge studies are made possible through the collaboration of major research and clinical practices, such as the partnership between TGen and Scottsdale Healthcare," said Dr. Mark Slater, Vice President of Research at Scottsdale Healthcare.

The authors remain particularly grateful to the patient and his family for their contribution to understanding more about this type of cancer and hope this dissemination of knowledge may help others.

Scottsdale Healthcare, Scottsdale Medical Imaging, and Sun Health Research Institute at Banner Healthcare contributed to this study, which was funded by the IBIS Foundation of Arizona and by the Scottsdale Healthcare Foundation.

Read the study at: http://dx.plos.org/10.1371/journal.pone.0045614.

###

About the Virginia G. Piper Cancer Center at Scottsdale Healthcare

The Virginia G. Piper Cancer Center at Scottsdale Healthcare opened in 2001 as the first major cancer center in greater Phoenix, offering comprehensive cancer care and research through Phase I clinical trials, diagnosis, treatment, prevention and support services in collaboration with leading researchers and community oncologists. The Scottsdale Healthcare cancer program holds Accreditation with Commendation from the Commission on Cancer of the American College of Surgeons. Scottsdale Healthcare is the nonprofit parent organization of the Virginia G. Piper Cancer Center at Scottsdale Healthcare, Scottsdale Healthcare Research Institute, Scottsdale Healthcare Osborn Medical Center, Scottsdale Healthcare Shea Medical Center and Scottsdale Healthcare Thompson Peak Hospital. For more information, visit www.shc.org.

Press Contact:

Keith Jones
Public Relations Director
Virginia G. Piper Cancer Center at Scottsdale Healthcare
480-323-1383
kjones@shc.org

About TGen

The Translational Genomics Research Institute (TGen) is a Phoenix-based non-profit organization dedicated to conducting groundbreaking research with life changing results. Research at TGen is focused on helping patients with diseases such as cancer, neurological disorders and diabetes. TGen is on the cutting edge of translational research where investigators are able to unravel the genetic components of common and complex diseases. Working with collaborators in the scientific and medical communities, TGen believes it can make a substantial contribution to the efficiency and effectiveness of the translational process. For more information, visit: www.tgen.org.

Press Contact:

Steve Yozwiak
TGen Senior Science Writer
602-343-8704
syozwiak@tgen.org


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


TGen and Scottsdale Healthcare report first study of clonal evolution in Maxillary Sinus Carcinoma [ Back to EurekAlert! ] Public release date: 28-Sep-2012
[ | E-mail | Share Share ]

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute

Examination of sinus cavity tumor provides potential roadmap for rare cancer treatments

PHOENIX, Ariz. Sept. 28, 2012 Knowing how tumors evolve can lead to new treatments that could help prevent cancer from recurring, according to a study published today by the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare.

TGen researchers tracked several years of tumor evolution in a 47-year-old male patient with maxillary sinus carcinoma (MSC), a rare cancer of the sinus cavities beneath the cheeks that often requires surgical removal that is disfiguring. Fewer than half of MSC patients live more than 5 years after diagnosis.

"The ability to characterize clonal evolution of this rare cancer and identify its Achilles' heel can significantly impact treatment, leading to more personalized medicine," according to the study published today in the journal PLOS ONE.

Clonal evolution refers to the often-rapid genetic changes that occur in cancer cells, which continually mutate and, thus, frequently resist anti-cancer drug compounds intended to destroy them.

"If we can understand the genomic basis of how this cancer evolves, perhaps we can find new treatments that could help improve the longevity and quality of life for patients," said Dr. Glen Weiss, Clinical Associate Professor at TGen, and Director of Thoracic Oncology at Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, a partnership with TGen. Dr. Weiss is one of the study's senior co-authors.

MSC represents nearly four of every five cases of paranasal sinus cancers, which grow rapidly and invade nearby tissues but also are usually slow to spread to distant sites. Patients usually die from a local recurrence of the tumor, even after aggressive treatment.

"This is the first report to study the clonal population of MSC arising in longitudinal samples from the same patient," the study said. "One of the aims of this study was to closely follow disease progression and the clonally evolving metastases for molecular profiling and accumulation of data for future use in development of personalized treatment."

The patient in the study received conventional treatment, which included surgical removal of his tumors, radiation therapy and chemotherapy, and participation in a clinical trial.

Over time, however, the cancer spread to his upper right lung, lower left lung, left kidney, brain and part of his intestine. He eventually was hospitalized, received hospice care and prior to passing away gave permission to have his cancer studied after death in a rapid autopsy research program.

"Because his cancer resumed growth despite several courses of systemic chemotherapy and radiation therapy, we speculated that acquired secondary genetic changes evolved with the evolution of resistance to these therapies," said Dr. Michael Barrett, Associate Professor in TGen's Clinical Translational Research Division, and the study's other senior co-author.

Analysis of his tumors following surgeries, biopsies and autopsy revealed several genetic aberrations, including multiple copies of a region on chromosome 4q, which includes the KIT gene. KIT is an oncogene, a gene with the potential to cause cancer, and is a potential treatment target.

The authors suggest the results provide a unique description of how the drug resistant cancer cells replicate and progress to metastatic MSC. Additional findings included the loss of the gene PKP4, which is associated with increased tumor size.

"These results show that molecular analyses of patient samples can add to the information about the tumor and help us in tracking back the progression of the disease," the authors concluded. "Identification of selected genetic changes, and the biological processes they regulate arising in primary MSC tumors, will advance individualizing therapy and improve the outcome of patients with rare cancers."

"These kinds of cutting-edge studies are made possible through the collaboration of major research and clinical practices, such as the partnership between TGen and Scottsdale Healthcare," said Dr. Mark Slater, Vice President of Research at Scottsdale Healthcare.

The authors remain particularly grateful to the patient and his family for their contribution to understanding more about this type of cancer and hope this dissemination of knowledge may help others.

Scottsdale Healthcare, Scottsdale Medical Imaging, and Sun Health Research Institute at Banner Healthcare contributed to this study, which was funded by the IBIS Foundation of Arizona and by the Scottsdale Healthcare Foundation.

Read the study at: http://dx.plos.org/10.1371/journal.pone.0045614.

###

About the Virginia G. Piper Cancer Center at Scottsdale Healthcare

The Virginia G. Piper Cancer Center at Scottsdale Healthcare opened in 2001 as the first major cancer center in greater Phoenix, offering comprehensive cancer care and research through Phase I clinical trials, diagnosis, treatment, prevention and support services in collaboration with leading researchers and community oncologists. The Scottsdale Healthcare cancer program holds Accreditation with Commendation from the Commission on Cancer of the American College of Surgeons. Scottsdale Healthcare is the nonprofit parent organization of the Virginia G. Piper Cancer Center at Scottsdale Healthcare, Scottsdale Healthcare Research Institute, Scottsdale Healthcare Osborn Medical Center, Scottsdale Healthcare Shea Medical Center and Scottsdale Healthcare Thompson Peak Hospital. For more information, visit www.shc.org.

Press Contact:

Keith Jones
Public Relations Director
Virginia G. Piper Cancer Center at Scottsdale Healthcare
480-323-1383
kjones@shc.org

About TGen

The Translational Genomics Research Institute (TGen) is a Phoenix-based non-profit organization dedicated to conducting groundbreaking research with life changing results. Research at TGen is focused on helping patients with diseases such as cancer, neurological disorders and diabetes. TGen is on the cutting edge of translational research where investigators are able to unravel the genetic components of common and complex diseases. Working with collaborators in the scientific and medical communities, TGen believes it can make a substantial contribution to the efficiency and effectiveness of the translational process. For more information, visit: www.tgen.org.

Press Contact:

Steve Yozwiak
TGen Senior Science Writer
602-343-8704
syozwiak@tgen.org


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-09/ttgr-tas092712.php

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BBcode, for forum posts and signatures:

--> Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.
Welcome to "Dreams & Games"

So here is where you RESERVE your spots or ask questions. . . Don't hesitate sharing ideas or what you're not liking ^^ I don't bite.
I hope you're all interested and willing to stick to the RP ^^

Thank you!!!!

Last edited by Green~Apple on Wed Sep 26, 2012 1:04 pm, edited 1 time in total.
User avatar
Green~Apple
Member for 0 years



I would like to reserve on of the females. This is interesting.

Lovely day we're having isn't it?

User avatar
Miss_Dreamer
Member for 0 years


Please could I reserve a male?

User avatar
Monochrome
Member for 2 years


Your places are reserved ^^ glad you're interested ;)

User avatar
Green~Apple
Member for 0 years


This looks very interesting! But before I make a decision, I was wondering if there was a post/word minimum or maximum? I checked the rules for it, but I literally just woke up and my vision is blurry so I might have missed it ^^" Unless there isn't one! Which is fine. I'm just making sure of something.

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Spectrum
Member for 1 years


I would like to reserve a female please?

Its better to ask forgiveness... than permission

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blondegamer
Member for 3 years


@- Spectrum:: Yeah there's no maximum or minimum of character to be written as long as the posts and character sheets are interesting I will accept it all ^^

@- blondegamer:: You got it!!!

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Green~Apple
Member for 0 years


Hmm.. Well! It's been a while since I was in one of those, so I'll give it a try ^^ May I reserve the last male please?

User avatar
Spectrum
Member for 1 years


So.

Im working on my character skeleton. However I have to be at work soon. So I will have it in to you tonight :D

If that is still cool

User avatar
blondegamer
Member for 3 years


I submitted Finch~ I hope he's okay-ish

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Monochrome
Member for 2 years


Can I have the last female spot, please?

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Horseygirl
Member for 3 years



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Wednesday, September 26, 2012

Etherpad Now Baked Into Social Project Management App Wrike

wrike_logoSocial project management software-as-a-service Wrike released a big update today, including in-line integration of the open source text editor Etherpad. The idea is that instead of attaching documents to a task, the task becomes the document, enabling users to actually do work in the same place they manage tasks.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/1U7mRBsgct0/

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